Metabolomics Detection
Our advanced untargeted GC-MS and LC-MS based metabolomics platforms lead to the most comprehensive detection across diverse compounds classes of d-spectrum detection across diverse compound classes and metabolic pathways.
With high-resolution profiling of both known and novel metabolites, you gain powerful insights for data-driven research—including mathematical modeling, crop breeding programs, and biomarker discovery.
In metaSysX we make a lot of effort to detect as many compounds as possible.
We have experience with almost all types of samples and know exactly how to prepare them to get the optimal results. We invest the time in testing of your precious samples to obtain the signal which enables detection of highest level of annotation.
To detect your compound of interest, additionally to the standard extraction method on request we perform alternative metabolite extractions.
Coupling of mass spectrometers to ultra-high pressure liquid chromatography further reduces the complexity and increases the number of detected features.
Derivatization of polar and hydrophobic compounds prior gas chromatography-mass spectrometry increases the pool of detectable compounds.
We perform two-phase liquid-liquid (mtbe:methanol:water) extraction which enables separation of hydrophobic and hydrophilic compounds described in Salem et al (Plant.Methods. 2016 45 (12) and Salem et al. (J Vis Exp . 2017, doi: 10.3791/55802). This reduces the complexity of samples and increases the metabolome coverage reflected in number of detected compounds.
We are open to adjust, optimize or customize other extraction methods which are more suitable and efficient for compounds of interest and different types od samples. Example: we performed highly efficient Tannins extraction by heating up the seeds and using more suitable organic solvent. For phytohormones we have a separate more efficient extraction method.
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